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Safron & Sage
Cristin D. Smith
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Safron & Sage

Restore hormonal balance and vitality with personalized TRT and peptide therapies, guided by expert practitioners.
12 Years of Experience
MD on Staff
Accepting new patients?
Last updated 5/16/2025 at 08:45 PM
Yes
Saffron & Sage is a members-only holistic health club and wellness center located in San Diego, California. The clinic offers a comprehensive range of integrative services, including naturopathic medicine, acupuncture, IV therapy, massage therapy, nutritional counseling, and advanced diagnostic testing. By combining modern evidence-based practices with ancient healing traditions, Saffron & Sage addresses the physical, emotional, and spiritual dimensions of health. The clinic caters to diverse populations, including women, men, and LGBTQIA+ individuals, and specializes in treating hormonal imbalances, autoimmune disorders, digestive issues, and chronic fatigue. Personalized care plans focus on identifying and addressing root causes to promote long-term wellness.
Client satisfaction:
Very High
How we determine this score?
Every rating you see is the product of a two-step process that blends data science with human clinical insight:
  1. Comprehensive review sweep We collect every publicly available patient review we can find—Google, Yelp, Healthgrades, ZocDoc, Facebook, Instagram, TikTok, Reddit, forums, and more. Duplicate or spam entries are filtered out, and each review is time-stamped so that newer feedback carries more weight.
  2. 13-factor sentiment analysis + expert audit A custom language-model pipeline scores each review across the 13 dimensions patients care about most:
    Friendliness | Professionalism | Responsiveness | Accessibility | Clarity of Explanations | Willingness to Listen | Personalization of Treatment | Billing Transparency | Value | Recurring Praise | Recurring Complaints | Side-Effect Education | Diet/Nutrition Guidance
    The algorithm converts raw language into numerical sentiment, flags outliers, and spots consistent themes. Finally, a board-certified clinician reviews the automated output to ensure medical-grade accuracy and context.
The result is a single, easy-to-read satisfaction bar that reflects real patient experience, not marketing copy. By combining transparent methodology, physician oversight, and continuously updated data, we deliver a score you can trust and that meets standards for authoritative health review content.
What people are saying
Clients describe detailed assessments leading to highly tailored, integrative plans that blend labs, hormone optimization, acupuncture, and nutrition. Practitioners explain options in plain language, invite questions, and fine-tune therapy as feedback and results emerge, producing marked gains in energy, symptom relief, and overall wellbeing. Scheduling and follow-up are generally quick, yet some patients cite high prices, add-on fees, or membership pressure that blur the clinic’s value proposition.
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Safron & Sage
Safron & Sage primary physician
Sponsored
LIVV Natural & Med Spa
Client satisfaction: Very High
About Safron & Sage
Established in 2017, Saffron & Sage was founded with a mission to revolutionize healthcare through the integration of scientific and spiritual practices. The clinic emphasizes holistic, personalized care designed to empower individuals toward optimal well-being. Its team includes: Cristin: Spiritual Director, Founder + CEO Dr. Trupti: Chief Medical Officer Dr. Scott, DACM, L.Ac: Clinic Director, Doctor of Acupuncture & Chinese Medicine, Certified Massage Therapist Dr. Kolin, DACM, L.Ac: Doctor of Acupuncture & Chinese Medicine, Herbalist & Functional Medicine Practitioner Dr. Alexander: Naturopathic Doctor & Nutritionist Dr. Mahshid, DAOM, L.Ac: Doctor of Chinese Medicine, Holistic Primary Care Provider, Licensed Acupuncturist & Herbalist Darby: Holistic Practitioner: Massage & Holistic Esthetician Central to their approach is a commitment to treating the whole person—mind, body, and spirit—and fostering a supportive, collaborative healing environment. Saffron & Sage’s broad spectrum of services and educational resources aim to nurture preventive care and sustainable health practices within its community.
What Makes Safron & Sage Unique
Saffron & Sage distinguishes itself through its exclusive membership model, which blends modern diagnostic methods with traditional healing arts. Annual memberships start at $9,600, providing members with unparalleled access to holistic healthcare services at predictable, locked-in rates. Membership grants patients access to a diverse array of treatments, from acupuncture to nutritional counseling, tailored to individual health goals. Additionally, the clinic prioritizes community involvement and patient education, regularly offering events and workshops. This unique combination of comprehensive, integrated services ensures a cohesive wellness journey for each patient.
Why Choose Safron & Sage
Patients select Saffron & Sage for its holistic approach and personalized attention dedicated to uncovering and addressing underlying health issues. Positive patient testimonials highlight the compassionate care and transformative outcomes achieved through the clinic’s treatments. Practitioners are noted for their empathy and attentiveness, creating an environment where patients feel heard and supported. The integrative care model, combining multiple therapeutic modalities, ensures a balanced and effective approach to health and wellness.
Philosophy of Care at Safron & Sage
The care philosophy at Saffron & Sage is built on the principle that true health involves harmony between mind, body, and spirit. The clinic integrates ancient medical traditions with contemporary evidence-based techniques to craft individualized treatment plans. Central to their philosophy is balancing Yin and Yang energies to restore internal harmony. The clinic emphasizes preventive care, patient empowerment, and education, encouraging individuals to actively engage in their own wellness journey. Treatment planning focuses on long-term health outcomes, adapting dynamically to patient needs over time.
Meet the team
FOUNDER & CEO
Cristin D. Smith
Cristin D. Smith is a visionary serial entrepreneur dedicated to transforming the healthcare industry through holistic wellness and integrative practices. Beginning her career in Financial & Insurance Services immediately after high school, Cristin swiftly rose through the ranks as a top producer, manager, and Vice President of Sales & Marketing. Driven by her entrepreneurial spirit, she co-founded a successful boutique brokerage firm before transitioning her passion into community development and social enterprise. A health crisis during a six-month sabbatical in Mexico profoundly reshaped Cristin's personal and professional trajectory, inspiring her to seek out holistic healthcare providers, therapeutic practices, and non-toxic wellness solutions. This transformative experience led to the founding of her acclaimed social enterprise, Saffron & Sage. As CEO and Spiritual Director of Saffron & Sage, Cristin skillfully blends ancient healing traditions with contemporary medical insights, emphasizing holistic wellness that nourishes the mind, body, and spirit. Cristin pursued her certification as a Spiritual Director through Loyola Marymount University and is also trained as a 3rd Degree Reiki Practitioner and Breathwork Instructor. Her expertise lies in facilitating profound individual growth and healing, guiding clients through their personal journeys with compassion, depth, and discernment. Cristin's influential work has earned recognition from numerous esteemed publications and organizations. She has been featured in outlets ranging from Forbes to Modern Luxury Magazine, and was recently honored as one of San Diego’s Top 22 Most Influential Leaders and recognized among the Top 40 Under 40 by the San Diego Business Journal. Under her leadership, Saffron & Sage has garnered multiple prestigious awards, including recognition as one of the Top 10 Spas by Conde Nast Traveler Magazine.
Dr. Trupti Gokani, MD
Dr. Trupti Gokani, MD, is an esteemed, award-winning neurologist renowned for integrating modern medical practices with ancient healing traditions. She has significantly advanced the field of headache treatment through her innovative, integrative approach, addressing the intricate connections between mind, body, and spirit. Dr. Gokani earned her medical degree from the University of Illinois at Chicago, where she completed her neurology training, served as Chief Resident, and obtained additional post-doctoral certification as a Master Clinical Psychopharmacologist. Her passion for holistic patient care has driven her to pursue further certifications in Ayurvedic medicine, Functional Medicine, and Transcendental Meditation, as well as board certification from the American Board of Neurology & Psychiatry. An accomplished educator and speaker, Dr. Gokani frequently lectures on topics including headaches, mood disorders, insomnia, adrenal fatigue, hormonal imbalances, and adult attention deficit disorder. Her expertise has led her to engagements with prestigious organizations such as Pfizer and media platforms alongside health influencers like Dr. Oz. Dr. Gokani is also the author of "The Mysterious Mind," a compelling exploration of the deeper purposes behind pain and the transformative power of understanding the mind-body-spirit connection. Her work continues to inspire patients and professionals alike to embrace holistic wellness for profound and lasting health outcomes.
Dr. Scott McFarlane, DACM, L.Ac
Dr. Scott McFarlane, DACM, L.Ac, CMT, is a passionate advocate and practitioner of Acupuncture and Traditional Chinese Medicine, driven by a deep commitment to helping others achieve a pain-free and balanced life. He holds a Doctorate in Acupuncture and Chinese Medicine and a Master of Science in Traditional Oriental Medicine from the Pacific College of Health and Science in San Diego, alongside an Associate of Applied Science in Holistic Health Science. As a board-certified and California-licensed acupuncturist and herbalist, Dr. Scott brings extensive expertise to his practice, complemented by his credentials as a Certified Massage Therapist and Reiki Master. His integrative, results-driven approach incorporates diverse healing modalities, including Qigong meditation, Asian Bodywork Therapy, and customized herbal medicine, to promote profound healing and lasting transformation. Outside his professional practice, Dr. Scott enjoys exploring his creative side through music, particularly playing the djembe drums and various guitars, spanning acoustic, electric, and classical styles.
Dr. Kolin Durrant, DACM, L.Ac.
Dr. Kolin Durrant, DACM, L.Ac., is an accomplished Eastern Medicine Doctor, Acupuncturist, Herbalist, Functional Medicine Practitioner, and dedicated wellness advocate. He earned his Doctorate of Acupuncture and Chinese Medicine and a Master of Science in Traditional Oriental Medicine from Pacific College of Health and Science, graduating with honors. Dr. Kolin’s personal health journey during his graduate studies profoundly influenced his professional path, prompting extensive advanced training in functional medicine. He specializes in thyroid health, autoimmune conditions, chronic illnesses, digestive health, and comprehensive wellness care. Dr. Kolin employs an integrative approach, utilizing acupuncture, functional medicine, herbal formulas, nutraceuticals, cupping, gua sha, therapeutic massage, dietary and lifestyle counseling, and energetic healing modalities. His primary focus is addressing underlying causes to restore balance and significantly enhance his patients' quality of life. In his personal life, Dr. Kolin cherishes being a devoted father to two children and grandfather to three wonderful grandsons. He enjoys leisure activities such as sailing, camping, and rock/gem hounding, particularly valuing time spent outdoors with family. With his comprehensive expertise, compassionate approach, and genuine commitment, Dr. Kolin is dedicated to empowering each individual on their path toward optimal health and vitality.
Dr. Alexander Aponte-Davila
Dr. Alexander Aponte-Davila is a dedicated Naturopathic Doctor and Nutritionist whose comprehensive academic and clinical background equips him to provide exceptional holistic primary care. He earned his Master's degree in Health Science Nutrition from the University of Puerto Rico Medical Health Science Campus, followed by a Doctorate in Naturopathic Medicine from Bastyr University Washington. Furthering his expertise, Dr. Alexander completed a rigorous two-year general Naturopathic Medicine Residency at Bastyr University California and is currently advancing his training with a two-year Integrative Medicine Fellowship at the Academy of Integrative Health & Medicine in La Jolla, CA. Dr. Alexander specializes in an integrative approach to conditions such as metabolic syndrome, weight management, endocrine and neurological disorders, mental health challenges, gastrointestinal conditions, nutrient deficiencies, chronic pain, and chronic infections. Fluent in both Spanish and English, he is committed to connecting authentically with diverse patient populations. His holistic approach incorporates Functional Laboratory Testing, IV Therapy, and Hormone Replacement, underscoring his belief in empowering patients through education and creating supportive healing environments. Outside of clinical practice, Dr. Alexander embraces wellness through activities such as hiking, working out, playing basketball, journaling, cooking, and engaging with music and podcasts—reflecting his balanced and integrative philosophy towards health and life.
Dr. Mahshid Mireskandari, DAOM, MTOM, L.Ac.
Dr. Mahshid Mireskandari, DAOM, MTOM, L.Ac., is a highly skilled practitioner specializing in Acupuncture and Herbal Medicine. She earned both her Master's and Doctorate degrees from Emperor’s College of Traditional Chinese Medicine, recognized as the premier institution in California and second nationwide. Dr. Mahshid's extensive training incorporates a diverse range of techniques from Japanese, Korean, and Classical traditions, allowing her to deliver personalized care tailored specifically to each patient's unique needs. Her clinical experience is enriched by specialized externships, including working under Dr. Robert Chu, PhD, at the Roy and Patricia Disney Family Cancer Center at Providence Hospital, where she provided supportive care for patients undergoing cancer treatments. Additionally, she honed her expertise assisting Dr. Atsuki Maeda, DAOM, in his practice dedicated to stroke recovery. Dr. Mahshid is dedicated to identifying and addressing root causes of health imbalances, particularly sleep disturbances and anxiety disorders. She passionately advocates holistic and natural treatments for skin conditions, combining Chinese Herbs, Facial Acupuncture, and Microneedling to achieve comprehensive results. Her integrated approach reflects her commitment to enhancing patients' well-being through both internal and external therapeutic strategies.
Client Satisfaction Analysis
We’ve collected every publicly available patient review we can find and analyzed them across 13 dimensions.
Select to learn more
Clients describe detailed assessments leading to highly tailored, integrative plans that blend labs, hormone optimization, acupuncture, and nutrition. Practitioners explain options in plain language, invite questions, and fine-tune therapy as feedback and results emerge, producing marked gains in energy, symptom relief, and overall wellbeing. Scheduling and follow-up are generally quick, yet some patients cite high prices, add-on fees, or membership pressure that blur the clinic’s value proposition.
Overall Hormones.org score for this clinic
93
The Overall Hormones.org Score of Safron & Sage places it in the bottom 48.2% of all hormone optimization clinics in the San Diego area.
Lower Quartile Lower Average Upper Average Upper Quartile Top 10%
What this means
Clinic scores follow a bell curve: most clinics cluster near the middle, while very low or very high scores become progressively rarer toward the edges.
How we determine this?
Category
Description
Weight
Review Sentiment Quality
Tone and trust language in the most recent 10-20 reviews
25%
Review Sentiment + Rating
Adjusted for inflation; not linear
10%
MD-Led Practice
Is the clinic led by a visible MD or board-certified physician?
10%
Estimated Years in Business
Based on site language, domain age and review timeline
10%
Specialization in Hormone Therapy
Is hormone optimization a core offering or a secondary add-on?
10%
Provider Relationship Model
Small, consistent provider model vs high-volume or anonymous feel
10%
Unique Differentiators
TRT + HRT + GLP-1s + peptides = strong depth
10%
Treatment Breadth
TODO: Add my description to this part
10%
Negative Flags Penalty
Subtract 5-10% for patterns like billing issues, cold tone, rushed care
-10%
Billing and Insurance
Billing
Saffron & Sage operates as a direct-pay clinic and does not accept traditional insurance. Patients should contact the clinic directly for additional information regarding billing options and membership details.
Insurance
Traditional insurance plans are not accepted; however, Saffron & Sage supports the use of HSA, FSA, and LSA funds. Patients should contact the clinic directly for further details on utilizing these accounts.
What New Patients Can Expect at Safron & Sage
New patients at Saffron & Sage start with a thorough consultation, involving a detailed health history review, wellness goal setting, and potentially diagnostic testing and integrative examinations. Based on this initial assessment, a tailored care plan is designed, incorporating therapies such as acupuncture, IV treatments, and nutritional counseling. Care plans emphasize patient collaboration, comfort, and goals. Follow-up visits track progress and adjust treatment plans as necessary, ensuring responsive and adaptive care.
FAQs about Safron & Sage
What is Saffron & Sage’s approach to healthcare?
Saffron & Sage offers a holistic, integrative model that combines conventional and natural therapies to address physical, emotional, and spiritual health. Their care model emphasizes personalized treatment plans, functional lab testing, and collaboration among practitioners to support long-term wellness.
What hormone-related therapies are available at Saffron & Sage?
Hormone-related therapies at Saffron & Sage include testosterone replacement therapy (TRT), progesterone therapy, peptide therapy, and acupuncture for endocrine support. These services are designed to address hormonal imbalances and promote overall well-being.
Who is eligible for testosterone replacement therapy at Saffron & Sage?
Testosterone replacement therapy is offered to individuals experiencing symptoms of low testosterone, such as decreased energy, reduced muscle mass, low libido, and mood changes. Eligibility is determined through comprehensive lab testing and a medical evaluation.
What are the benefits of progesterone therapy at Saffron & Sage?
Progesterone therapy may help regulate menstrual cycles, relieve menopause symptoms, support fertility, and balance estrogen levels. It is especially beneficial for individuals with hormonal imbalances due to perimenopause, menopause, or chronic stress.
How does Saffron & Sage support women's hormonal health?
Saffron & Sage provides acupuncture, nutritional counseling, herbal medicine, and lifestyle coaching to address conditions such as PCOS, PMS, menopause symptoms, and fertility challenges. These services aim to restore hormonal balance and enhance wellness.
Trust and Safety Certifications
Provider License & Certifications
Trupti Gokani - California Medical Board Certification
Issuer: Medical Board of California
License No: C 54417
Medical School Name: University of Illinois College of Medicine
Name: GOKANI, TRUPTI BINAL
License Type: Physician and Surgeon C
Graduation Year: 1997
Primary Status: License Renewed & Current
Scott McFarlane - California Acupuncture Board
Name: MCFARLANE, SCOTT CULLOP
License No: 19502
License Type: Licensed Acupuncturist
License Status: Clear
Issuance Date: July 14, 2022
Alexander Aponte-Davila - California Board of Naturopathic Medicine License
Name: Aponte Davila, Alexander
Issuer: California Board of Naturopathic Medicine
License Type: Naturopathic Doctor
Issuance Date: October 19, 2021
Primary Status: License Renewed & Current
License No: 1294
Provider Registrations
Trupti Gokani - National Provider Identifier
NPI Number: 1780638205
Numeration Date: 2006-05-20
NPI Type: NPI-1 Individual
Status: Active
Scott McFarlane - National Provider Identifier
NPI Number: 1477288371
Numeration Date: 2022-07-24
NPI Type: NPI-1 Individual
Status: Active
Alexander Aponte-Davila - National Provider Identifier
NPI Number: 1649940784
Numeration Date: 2021-09-20
NPI Type: NPI-1 Individual
Status: Active
Clinic location
Map icon
Saffron & Sage is ideally located at 2555 State St, San Diego, CA, near the intersection of State Street and Laurel Street. Situated in vibrant Little Italy, the clinic is within walking distance of popular landmarks like Waterfront Park, Little Italy Mercato Farmers’ Market, and numerous local restaurants. The clinic entrance is easily identifiable at street level, clearly marked and visible upon arrival from State Street.
Map showing location of Safron & Sage
Safron & Sage
2555 State Street suite b3
San Diego, CA 92101, US
Saffron & Sage in San Diego provides convenient free street parking along State Street and surrounding side streets. Handicap-accessible parking spaces are available nearby. Additional paid parking lots and garages are within walking distance, typically charging hourly fees without validation. Arriving a few minutes early is recommended to secure the best street parking closest to the clearly marked clinic entrance on State Street.
Clinic Hours
Mon 8:00 AM - 8:00 PM
Tue 8:00 AM - 8:00 PM
Wed 8:00 AM - 8:00 PM
Thu 8:00 AM - 8:00 PM
Fri 8:00 AM - 8:00 PM
Sat 8:00 AM - 2:00 PM
Sun 8:00 AM - 2:00 PM
Safron & Sage at a glance
Accepting New Patients
Yes
Offers in Person Care
Yes
Offers Telehealth
Yes
Language Spoken
English
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Safron & Sage